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KMID : 0357220010130010041
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Journal of Korean Society Physical Therapy
2001 Volume.13 No. 1 p.41 ~ p.48
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The Effect of Cold Application on Ischemia-Reperfusion Injury to Quadriceps Femoris Muscle of the Rats
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Abstract
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The purpose of this study was to investigate the effect of cold application on ischemia-reperfusion injury to quadriceps fomoris muscle of the hind limbs of the rats. Nine weeks old male Sprague-Dawley white rats were divided into three groups : 1) control(only ischemia-reperfusion), 2) cold application before reperfusion(PreCold), 3) cold application after reperfusion(PostCold). All groups were 30 minute, 1 hour, 3 hours reperfusion after 2 hours ischemia with clamping abdominal artery, and investigate superoxide dismutase(SOD) immunohistochemical reaction for quadriceps femoris muscle of right hindlimb.
SOD immunohistochemical reaction of experimental groups were more than the control group. Especially, SOD immunohistochemical reaction of PreCold were-less than the Post Cold.
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